Imodium for Dogs: Uses, Dosage, & Side Effects

Imodium is a medication that can be used to treat dogs with diarrhea. Imodium is actually a brand name for a drug called Loperamide. It works by slowing down movement in the intestines, allowing the intestinal walls to absorb electrolytes and water and preventing food from moving through the intestines too quickly.

Even though it’s sold as an over-the-counter medicine, you shouldn’t give it to your dog unless your veterinarian says it’s safe. Some dogs have a hard time breaking down the drug, and certain medical conditions may be worsened by Imodium.


Closely follow your vet’s instructions for dosage and administering the medication. Here’s what you should know about the uses, dosage, and side effects of Imodium for dogs.

Uses of Imodium for dogs

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Imodium is primarily used to treat diarrhea in dogs, though it can also be used to treat acute colitis, irritable bowel syndrome, and malabsorption/maldigestion.

However, dogs should not take it to treat diarrhea that may be caused by an infection or by ingestion of toxins like poisonous mushrooms. Diarrhea is the body’s natural method of removing these harmful substances. Therefore, stopping the diarrhea might actually not be beneficial in those cases.

This is why you should consult your vet so they can determine the cause of your dog’s diarrhea and prescribe treatment accordingly.

Dosage of Imodium for dogs

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The following is a guideline for typical use of the drug in dogs. It must not replace your veterinarian’s advice for your individual pet.

The usual dosage of Imodium for dogs depends on which form of the medication you are using.

With the liquid form of Imodium A-D, dogs are usually given 0.3 to 0.6 mL per pound of weight two to three times per day. This is generally poured over dogs’ food.

For Imodium A-D caplets or EZ Chews, dogs should usually take one 2 mg caplet or chew for every 25 to 50 pounds of body weight two or three times per day.

Imodium Multi-Symptom Relief has 2 mg of Loperamide, but it also contains simethicone. This drug is also generally safe for dogs, and dogs should get one pill for every 25 to 50 pounds of weight.

Your vet might wish to alter the dosage based on your dog’s reaction to the drug or their medical history. Follow your vet’s instructions closely.

Side effects of Imodium in dogs

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One possible side effect of Imodium in dogs is sedation. This is especially true for many herding breeds, including Collies, German Shepherds, Australian Shepherds, many kinds of Sheepdogs, Longhaired Whippets, Silken Windhounds, and Skye Terriers.

These breeds are more likely to have a genetic mutation called an MDR1 mutation. This makes it harder for their bodies to remove toxic substances from their brains. You can ask your vet to test your dog for this mutation.

Other possible side effects include vomiting, soft stools, constipation, gas, weight loss, and bloody diarrhea.

If you give this medication your dog to treat diarrhea and symptoms don’t improve within two days, then you must call your vet. You should not give it to your dog for more than five consecutive days.

Tell your vet about any other medications or medical conditions your dog has, as these can interact poorly. The drug may not be right for very young or old dogs or dogs who are pregnant or nursing.

Always consult your vet before giving your dog medication, even if it is over-the-counter, and follow their instructions carefully.

Related: Pepto Bismol For Dogs

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